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Products Monoclonal Anti-N-Cadherin
| Catalogue number: | MA1067 |
| Price: | $200.00 |
| Reactivities: | Human, Mouse, Rat, Chicken/Bird, Rabbit |
| Applications: | Immunohistochemistry - frozen, Western Blot |
| Size: | 100ug/vial |
| Gene: | Human(1000), Mouse(12558), Rat(83501) |
| Swiss prot: | Human(P19022), Mouse(P15116), Rat(Q9Z1Y3) |
| Form: | Lyophilized |
| Format: | 1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, the antibody concentration will be 100ug/ml. |
| Target synonym: | CDHN; NCAD; CD325; CDw325; Neural cadherin |
| Storage temp: | At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing. |
| Primary protein: | Cadherin-2 |
| Scientific background: | N-cadherin (NCAD) is a member of the cadherin cell-cell adhesion receptor family that includes P-, E-, and R-cadherin and liver cell adhesion molecule (L-CAM). N-Cadherin,, also known as Cadherin-2, encodes a 907-amino acid protein that includes a 159-amino acid signal sequence. Human and mouse nucleotide sequences are 96% identical. Mouse Ncad gene consists of 16 exons dispersed over more than 200 kb of genomic DNA. Human N-cadherin gene contains 16 exons and its sequence is highly similar to both the mouse NCAD gene (including the large first and second introns) and other cadherin genes. N-cadherin is mapped to 18q11.2. Cadherin regulates dendritic spine morphogenesis. |
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