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mGluR-7 (Ser862) Antibody
ABBIOTEC

Supplier:

ABBIOTEC

Cat no: 252558

mGluR-7 (Ser862) Antibody

The metabotropic glutamate receptor 7 (mGluR7) is a receptor for L-glutamate. L-glutamate is the major e, Xenopus/Amphibian,citatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors that have been divided into 3 groups on the basis of sequence homology,Porcineutative signal transduction mechanisms, and pharmacologic properties. A member of the Group III receptor class,Mouse,GluR7 inhibits the cyclic AMP cascade. PKC phosphorylation of serine 862 on mGluR7 has been shown to be critical for stabilizing receptor surface e, Xenopus/Amphibian,pression and promoting binding to the synaptic PDZ-domain-containing protein PICK1.

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SPECIFICATIONS

Catalog Number

252558

Size

0.1 ml

Applications

WB

Reactivities

Hum, Mouse, Bov, Ch/Bird, Rabbit, Xen/Amph

Format

Each vial contains 0.1 ml IgG in HEPES pH7.5, 150 mM NaCl, 0.01% BSA and 50% glycerol. Antibody was purified by immunogen affinity chromatography.

P Type

Rabbit Polyclonal Antibody,Porcinehosphospecific Antibody

Antigen

KLH-conjugated synthetic phosphopeptide encompassing a sequence surrounding Ser862 of rat metabotropic glutamate receptor 7.

Isotype

Rabbit IgG

Accession

P35400

Additional Info

Metabotropic glutamate receptor 7; mGluR7; Grm7; Gprc1g; Mglur7

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