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LEAF(TM) Purified anti-mouse/human CD44

LEAF(TM) Purified anti-mouse/human CD44

Cat no: 103033


Supplier: BioLegend
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CD44 is a 80-95 kD glycoprotein also known as Hermes, Pgp1, H-CAM, or HUTCH. It is expressed on all leukocytes, endothelial cells, hepatocytes, and mesenchymal cells. As B and T cells become activated or progress to the memory stage, CD44 expression increases from low or mid levels to high levels. Thus, CD44 has been reported to be a valuable marker for memory cell subsets. High CD44 expression on Treg cells has been associated with potent suppressive function via high production of IL-10. CD44 is an adhesion molecule involved in leukocyte attachment to and rolling on endothelial cells, homing to peripheral lymphoid organs and to the sites of inflammation, and leukocyte aggregation.
Catalogue number: 103033
Reactivities: Human, Mouse
Hosts: Rat
Applications: ELISA, Flow Cytometry, Immunohistochemistry, Immunoprecipitation
Size: 1 mg
Clone: IM7
Gene: 12505,960
Dilutions: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ? 0.25 microg per 106 cells in 100 microl volume. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer: The antibody solution should be stored undiluted at 4C. This LEAF(TM) solution contains no preservative; handle under aseptic conditions.
Concentration: 1 mg/ml
Antigen: Dexamethasone-induced myeloid leukemia M1 cells
Isotype: Rat IgG2b, kappa
Clonality: Monoclonal
Regulatory status: RUO
Shipping temp: Ambient RT
Storage temp: 4 C
Alternative names: Hermes, Pgp-1, H-CAM, HUTCH-1, ECMR III, gp85, Ly-24