logo
logo
Human Serum Aminopeptidase N

Cat no: 30801002

Human Serum Aminopeptidase N

Aminopeptidase N is a receptor for human coronavirus (Yeager et al. 1992); it has an important role in HIV entry (Pulido-Cejudo et al. 1997) and in the processing of peptide for presentation by antigen-presenting cells (Hansen et al. 1993). This peptidase was shown to be involved in the degradation of extracellular matrix in tumor invasions. Its levels are elevated in cancer subjects and correlate with tumor load, and thus, the enzyme is believed to play a role in angiogenesis (Saiki et al., 1993). The catalytic domain of CD13 faces the exterior of the plasma membrane and is anchored by a transmembranespanning domain, which is composed of N-terminal residues 9-32 (Shipp and Look, 1993). An N-terminal truncated major isoform of CD13 lacking residues 1-58 has been purified from normal human serum (Watanabe et al., 1998), but also a minor isoform 43-truncated CD13 (Kawai et al., 2001). The biological significance of this proteolytic cleavage mechanism is yet obscure.

Prices direct from B-BRIDGE INTERNATIONAL, INC

Quick response times

Exclusive Absave savings/discounts

SPECIFICATIONS

Catalog Number

30801002

Size

10 ug/ 50ul

Storage Temp

- 20 degree C

Shipping Temp

dry ice

Latest promotions

New brilliant antibodies, and new lower prices!For flow cytometry reagents in general, \"bright is better.\" The violet-excitable BD Horizon™ BV421 and...

Buy any polyclonal or monoclonal antibody from our extensive range of pre-made antibodies and for a limited time only receive a $50 discount!(T&C apply:...

We're so sure that you'll prefer Cayman Assay kits over your present brand that we're willing to give you a free assay kit to prove it!

For the past decade scientists have extensively used ATS secondary toxin conjugates to make their own targeted toxins for in vitro use.The ability to combine...

10% Discount on 2 Rabbit Polyclonal Antibody Service. With over 20 years experience, SDIX has developed into the premier US custom antibody producer,...

Did your supplier increase the price of Fetal Bovine Serum? Did they substitute the US Origin with USDA? Well say no more! Innovative Research is still...

Bulk Cytokines with Custom Vialing.20 - 50% off cytokines, growth factors, chemokines and more...For a limited time Cell Sciences is offering substantial...

Are you planning to have a customised antibody made for your research?Since 2000, Everest has been producing a catalog containing thousands of affinity...