Human Heat shock proteins 27 (Hsp 27) ELISA Kit 33 Kit (96 Wells)

Human Immunoglobulin A (IgA) is the most abundant antibody isotype in mucosal secretions and exists in two subclasses IgA1 and IgA2 (1). While circulating serum IgA1 occurs mainly in the monomeric 160 kDa form (2), mucosal secretary IgA2 is in dimeric form and serves as the first line of defense against microorganisms through immune exclusion (3). Selective IgA deficiency is the most common primary immunodeficiency observed by a maturation defect in B cells to produce IgA (4). IgA nephropathy is the primary glomerulonephritis characterized by IgA deposition in the kidney and associated with a dysregulation of the immune response (5-6).