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Hsp90 total

Hsp90 total

Cat no: SMC-149B


Supplier: StressMarq Biosciences Inc.
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This antibody detects both (A) and (B) forms of Hsp90 equally well.
Catalogue number: SMC-149B
Reactivities: Human, Mouse
Hosts: Mouse
Applications: ELISA, Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot
Size: 200ug
Clone: 4F3.E8
Accession: NP_001017963.2
Gene: 3320
Swiss prot: P07900
Dilutions: 1:2000 (WB)
Form: Protein G Purified
Storage buffer: PBS pH7.2, 50% glycerol
Concentration: 1mg/mL
Isotype: IgG1
Shipping temp: Blue Ice or 4
Storage temp: -20
Research area: Heat Shock
Certificate of analysis: 0.5 ug/mL of SMC-149 was sufficient for detection of Hsp90alpha in 20ug of heat shocked HeLa cell lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
Scientific background: HSP90 is an abundantly and ubiquitously expressed heat shock protein. It is understood to exist in two principal forms (A) and (B), which share 85% sequence amino acid homology. The two isoforms of Hsp90 are expressed in the cytosolic compartment (1). Des
Alternative names: Hsp84, Hsp86, Hsp90A, Hsp90AA1, Hsp90AB1, Hsp90B, HspC1, HspC2, HspCAL1, HspCAL4
References: 1. Nemoto, T. et al. (1997) J.Biol Chem. 272, 26179-26187. 2. Minami, Y, et al. (1991), J.Biol Chem. 266, 10099-10103. 3. Arlander SJH, et al. (2003) J Biol Chem 278, 52572-52577. 4. Pearl H, et al. (2001) Adv Protein Chem 59,157-186. 5. Neckers L, et al.