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HSF1

HSF1

Cat no: SMC-118D


Supplier: StressMarq Biosciences Inc.
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Detects an ~85kDa protein in unstressed cell lysates, and an ~95kDa protein in heat shocked cell lysates, corresponding to the molecular mass of inactive and active forms of HSF1 on SDS PAGE immunoblots.
Catalogue number: SMC-118D
Reactivities: Human, Mouse, Rat, Bovine, Guinea Pig, Hamster, Rabbit
Hosts: Rat
Applications: ELISA, Immunocytochemistry, Immunoprecipitation, Western Blot
Size: 100ug
Clone: 10H8
Accession: NP_005517.1
Gene: 3297
Swiss prot: Q00613
Dilutions: 1ug/ml was sufficient for detection of HSF1 by ECL immunoblot in 20ug of HeLa lysate.
Form: Protein G Purified
Storage buffer: PBS pH7.4, 50% glycerol
Concentration: 1mg/mL
Isotype: IgG1
Shipping temp: Blue Ice or 4
Storage temp: -20
Research area: Heat Shock
Certificate of analysis: 1 ug/mL of SMC-118 was sufficient for detection of HSF1 in 20ug of heat shocked HeLa cell lysate by ECL immunoblot analysis using Goat anti-rat IgG: HRP as the secondary antibody
Scientific background: HSF1, or heat shock factor 1, belongs to a family of Heat Shock transcription factors that activate the transcription of genes encoding products required for protein folding, processing, targeting, degradation, and function (2). The up-regulation of HSP (
Alternative names: HSTF1
References: 1.Cotto J.J., Fox S.G. and Morimoto R.I. (1997) J. Cell Science 110: 2925-2934. 2.Morano K.A. and Thiele D.J. (1999). Gene Expression 7 (6): 271-82. 3.Tanaka KI et al. (2007). JBC Papers Online Manuscript M704081200. 4.Morimoto R. I. (1998) Genes Dev 12: