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ESAT-6 Mycobacterium (11G4) Antibody
ABBIOTEC

Supplier:

ABBIOTEC

Cat no: 250322

ESAT-6 Mycobacterium (11G4) Antibody

ESAT-6 (6-kDa early secretory antigenic target) from Mycobacterium tuberculosis H37Rv (ATCC 27294) is a secreted tubercular protein that forms a dominant target for cell-mediated immunity in the early phase of infection. The deduced amino acid sequence indicates a molecular mass of 10 kDa. It is present in M. tuberculosis, virulent strains of M. bovis, and in M. flavescens,Mouse,. kansasii,Mouse,. marinum,and M. szulgai, but not in avirulent M. bovis BCG substrains. This antibody reacts with ESAT-6 in immunoblotting after SDS-PAGE of short-term culture filtrates of M. tuberculosis and virulent strains of M. bovis. The antibody cross-reacts with MPB64 (26 kDa) from certain BCG substrains, with the A, Bovine, and C components of the antigen 85 comple, Xenopus/Amphibian, and with MPT51.

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SPECIFICATIONS

Catalog Number

250322

Size

0.2 mg

Applications

WB

Format

Each vial contains 0.2 mg IgG in 0.2 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A/G affinity chromatography.

P Type

Mouse Monoclonal Antibody

Antigen

Purified protein derivative (PPD) of tuberculin from M. tuberculosis conjugated with thimerosal N-hydro, Xenopus/Amphibian,ysuccinimide ester and adsorbed to aluminum hydro, Xenopus/Amphibian,ide gel (4).

Isotype

Mouse IgG1/k

Accession

P0A564

Clonality

11 G4

Additional Info

6 kDa early secretory antigenic target

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