logo
logo
Cathepsin G

Cat no: 30600302

Cathepsin G

Polymorphonuclear leukocytes (PMNs) contain abundant amounts of antibacterial proteins and proteolytic enzymes within peroxidase-positive azuphil granules. Some of these proteins show a spectrum of antibiotic activities and are collectively termed serprocidins. These include the serine proteases elastase, cathepsin G, proteinase 3 and a protein termed azurocidin which lacks proteolytic activity. Several line of evidence suggest that enzymes released extracellularly by PMNs as cathepsin G play an important role in the tissue destruction (Groutas, 1987) associated with a number of inflammatory diseases (Malech and Gallin, 1987) such as emphysema, (Groutas, 1987), ARDS (Warshawski et al., 1986) glomerulonephritis (Johnson et al., 1988) and rheumatoid arthritis (Saklatvala and Barrett, 1980). Cathepsin G acts as potent agonist of human platelet activation (Selak et al., 1988) leading to their aggregation and is reported to be involved in the activation of proMMP-2 via mechanism requiring MT1-MMP.

Prices direct from B-BRIDGE INTERNATIONAL, INC

Quick response times

Exclusive Absave savings/discounts

SPECIFICATIONS

Catalog Number

30600302

Size

10 ug / 50 ul

Gene Id

1511

Storage Temp

- 20 degree C

Shipping Temp

dry ice

Latest promotions

New brilliant antibodies, and new lower prices!For flow cytometry reagents in general, \"bright is better.\" The violet-excitable BD Horizon™ BV421 and...

Buy any polyclonal or monoclonal antibody from our extensive range of pre-made antibodies and for a limited time only receive a $50 discount!(T&C apply:...

We're so sure that you'll prefer Cayman Assay kits over your present brand that we're willing to give you a free assay kit to prove it!

For the past decade scientists have extensively used ATS secondary toxin conjugates to make their own targeted toxins for in vitro use.The ability to combine...

10% Discount on 2 Rabbit Polyclonal Antibody Service. With over 20 years experience, SDIX has developed into the premier US custom antibody producer,...

Did your supplier increase the price of Fetal Bovine Serum? Did they substitute the US Origin with USDA? Well say no more! Innovative Research is still...

Bulk Cytokines with Custom Vialing.20 - 50% off cytokines, growth factors, chemokines and more...For a limited time Cell Sciences is offering substantial...

Are you planning to have a customised antibody made for your research?Since 2000, Everest has been producing a catalog containing thousands of affinity...