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BTK (7F12) Antibody
ABBIOTEC

Supplier:

ABBIOTEC

Cat no: 252705

BTK (7F12) Antibody

BTK (Tyrosine-protein kinase BTK) is a tyrosine kinase that plays a crucial role in B-cell ontogeny. Defects in BTK are the cause of , Xenopus/Amphibian,-linked agammaglobulinemia (, Xenopus/Amphibian,LA) also known as , Xenopus/Amphibian,-linked agammaglobulinemia type 1 (AGM, Xenopus/Amphibian,1) or immunodeficiency type 1 (IMD1). , Xenopus/Amphibian,LA is a humoral immunodeficiency disease which results in developmental defects in the maturation pathway of B-cells. Affected boys have normal levels of pre-B-cells in their bone marrow but virtually no circulating mature B-lymphocytes. This results in a lack of immunoglobulins of all classes and leads to recurrent bacterial infections.

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SPECIFICATIONS

Catalog Number

252705

Size

0.1 ml

Applications

IF, IHC

Reactivities

Hum, Mouse

Format

Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.

P Type

Mouse Monoclonal Antibody

Antigen

Purified recombinant fragment of BTK e, Xenopus/Amphibian,pressed in E. coli.

Isotype

Mouse IgG1

Accession

Q06187

Clonality

7F12H4

Additional Info

BTK; Tyrosine-protein kinase BTK; Bruton tyrosine kinase; Agammaglobulinaemia tyrosine kinase; ATK; B-cell progenitor kinase; BPK; AGM, Xenopus/Amphibian,1; ATK; BPK

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