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BRCA1 (Rodent) Antibody
ABBIOTEC

Supplier:

ABBIOTEC

Cat no: 251302

BRCA1 (Rodent) Antibody

Breast cancer type 1 susceptibility protein (BRCA1) is an E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. Defects in BRCA1 are a cause of susceptibility to breast cancer (BC).

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SPECIFICATIONS

Catalog Number

251302

Size

0.1 mg

Applications

IHC

Reactivities

Rabbit

Format

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

P Type

Rabbit Polyclonal Antibody

Antigen

KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of mouse BRCA1.

Isotype

Rabbit Ig

Accession

P48754

Additional Info

BRCA1; Breast cancer type 1 susceptibility protein homolog

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