anti-IGSF8 (mouse) antibody, rabbit serum

IGSF8 may play a key role in diverse functions ascribed to CD81 and CD9 such as oocytes fertilization or hepatitis C virus function and is thought to serve many other functions:May regulate proliferation and differentiation of keratinocytesMay be a negative regulator of cell motility: coordinates with CD81 to suppresses T-cell mobility, associates with CD82 to suppress prostate cancer cell migration, regulates epidermoid cell reaggregation and motility on laminin-5 with CD9 and CD81 as key linkers. May also play a role on integrin-dependent morphology and motility functions. May participate in the regulation of neurite outgrowth and maintenance of the neural network in the adult brain.