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Alpha A Crystallin

Alpha A Crystallin

Cat no: SMC-142B


Supplier: StressMarq Biosciences Inc.
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Detects (A)-crystallin at ~20kDa. Does not cross-react with (A)B-crystallin, (B)L-crystallin, (B)H- crystallin, ?-crystallin, Hsp25, Hsp27 or Hsp47 proteins.
Catalogue number: SMC-142B
Reactivities: Human, Mouse, Bovine
Hosts: Mouse
Applications: ELISA, Western Blot
Size: 200ug
Clone: 1H3.B8
Accession: NP_000385.1
Gene: 1409
Swiss prot: P02489
Dilutions: 1:2000 (WB)
Form: Protein G Purified
Storage buffer: PBS pH7.2, in 50% glycerol
Concentration: 1mg/mL
Isotype: IgG1
Shipping temp: Blue Ice or 4
Storage temp: -20
Research area: Chaperones&Trafficking
Certificate of analysis: 0.5ug/ml was sufficient for detection of 100ng purified alphaA crystalline by colorimetric immunoblot analysis using Goat Anti-Mouse IgG:HRP as the secondary.
Scientific background: The alpha-crystallins are major water-soluble lens structural proteins of the vertebrate eye that are related to the small heat shock protein family. The alpha-crystallins possess structural and functional similarities with Hsp25 and Hsp27 (1). Mammalian
Alternative names: Heat shock protein beta4, Acry 1, CRYA1, CRYAA, HspB4
References: 1. Merck K.B. et al. (1993) J Biol Chem. 268: 1046-1052. 2. Horwitz J. (1992) Proc Natl Acad Sci USA 89(21): 10449-10453. 3. Cobb B.A. and Petrash J.M. (2002) Biochemistry. 41: 483-490 4. Horwitz J. (2003) Exp Eye Res. 76: 145-153. 5. Bullard B. et al. (2